You are welcome to ask questions during the talk either by speaking up or typing in the chat.

Have your tried adding and removing gravity in the experiment?

Can you elaborate more on what the S1 and S2 compartments are and how we know where they correspond to on the chromosome?

Instead of usual sticky beads (LJ) you have harmonic constraints. How does it help? A heterogeneous sticky bead model in principle should be able to reproduce the contact map and subsequently a reliable 3D structure.

thanks. we will ask these questions as soon as possible.

we'll take questions at the end of the talk. please stay back after the hour (10-15 minutes) for informal Q&A (without recording).

Force will change the shape of the nucleus. What effects would this have on your experiments?

Thanks!